Shear Stiffness of Equine Synovial Membrane in Osteoarthritis And Response to 2.5% Injectable Polyacrylamide Hydrogel Treatment.

Presented at ICRS – 18th World Congress Boston, MA. 11-14th October 2025.

M.A. Wimmer, M.J. AbuAlia; Rush University Medical Center Chicago, IL/US

Purpose:

The synovial membrane plays an important role in osteoarthritis and is increasingly linked to both the development and progression of the disease. The objective of this study was to evaluate synovial membrane stiffness in a preclinical equine osteochondral fragment model of osteoarthritis, assessing the effects of intra-articular polyacrylamide hydrogel (2.5% iPAAG; Arthramid®, Contura®, Denmark).