Clinical Studies

Discover the Science Behind Arthramid® 2.5% iPAAG

Arthramid is used by veterinarians everyday around the world for the treatment of joint lameness in horses. Multiple published studies from high profile institutions, and treating thousands of equine patients across all equestrian disciplines, show that Arthramid is a safe and effective treatment for osteoarthritis and joint lameness in animals.

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Histologic and cytologic changes in normal equine joints after injection with 2.5% injectable polyacrylamide hydrogel reveal low-level macrophage-driven foreign body response

Lowe J, de Clifford L, Julian A, Koene M. Histologic and cytologic changes in normal equine joints after injection with 2.5% injectable polyacrylamide hydrogel reveal low-level macrophage-driven foreign body response. JAVMA 2024

A double-blinded positive control study

de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2021). A double-blinded positive control study comparing the relative efficacy of 2.5% polyacrylamide hydrogel (PAAG) against triamcinolone acetonide (TA) and sodium hyaluronate (HA) in the management of middle carpal joint lameness in racing Thoroughbreds.

A double-blinded positive control study comparing

Initial Estimates of Efficacy of Intra-Articular

Henrikson, M., Overgaard, A., and Bliddal, H. (2017). Initial Estimates of Efficacy of Intra-Articular 2.5% Polyacrylamide Hydrogel for the Treatment of Knee Osteoarthritis: An Observational Proof-of-Concept Study

Intra-articular polyacrylamide hydrogel

Bathe, A.P., Read, R.M., and Briggs, C. (2016). Intra-articular polyacrylamide hydrogel for the treatment of 20 horses with non-responsive osteoarthritis of the interphalangeal joints: a prospective study

Synovial incorporation of polyacrylamide hydrogel

Christensen, L., Illigen, K.E., Hansen, M., Sarvaa, R., and Conogham, P.G. (2016). Synovial incorporation of polyacrylamide hydrogel after injection into normal and osteoarthritic animal joints

Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel

de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2019). Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study

EQUINE WHITE PAPER

Veterinarians: Get your copy of our 24 page white paper today, covering Treatment of Joint Lameness, Pathophysiology, Manufacturing, Mechanism of Action, Clinical Safety and Putting it into Practice.

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CANINE WHITE PAPER

Veterinarians: Get your copy of our 21 page white paper today, covering Treatment of Joint Lameness, Pathophysiology, Manufacturing, Mechanism of Action, Clinical Safety and Putting it into Practice.

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Testimonials

Dr. Dan Carter

COUNTRYSIDE VETERINARY HOSPITAL - COVINGTON, GA

“Arthramid is a game changer for all equine athletes. It all starts in the synovium with synovitis and capsulitis, before we get to osteoarthritis. I routinely tell my horse owners, ‘save the synovium, save the joint’.”

Dr. Vern Dryden

BUR OAK SPORTS MEDICINE & LAMENESS, LEXINGTON, KY

“It’s given me another tool in my arsenal to effectively manage all stages of equine osteoarthritis, especially those horses with equine metabolic disease.”

Dr Marc Koene

TIERKLINIK LÜSCHE GMBH EQUINE HOSPITAL – NORTHER GERMANY

"We have injected over a thousand horses and have found it to be very safe. It has been a major game-changer in the way we treat OA in our patients.”

Dr Charley McColough

PALM BEACH EQUINE - WELLINGTON, FL

"By incorporating Arthramid into my practice, I’m able to use far fewer steroids while still achieving excellent results, which gives me greater peace of mind for the long-term well-being of the horses under my care."

Dr Bob Peters

MCKINLAY & PETERS EQUINE HOSPITAL - NEWMAN LAKE, WA

"In my opinion, it is efficacious, long-lasting and lower risk to cartilage than many alternatives."

Testimonials

Arthramid
Clinical Studies

Discover the Science Behind Arthramid® 2.5% iPAAG